Small Chloroquine Study Halted Over Risk of Fatal Heart Complications

Discussion in 'Coronavirus (COVID-19) News' started by HumbledPi, Apr 14, 2020.

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  1. Moolk

    Moolk Banned

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    There are risks with any medicine.

    This medicine has shown promise to the point that its been approved by the FDA.

    GJ President Trump!
     
  2. funblossom

    funblossom Newly Registered

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    I wish this is the cure for the disease. People have been working so hard for a solution! Good job.
     
  3. 557

    557 Well-Known Member

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    As a professional, what’s your opinion on the maniacal use of vents for C19 based on prior knowledge without any testing in actual C19 cases? Perhaps you can provide the clinical trials in C19 patients that the use of vents was based on.

    Who takes the blame for those harmed and killed by incorrect use of vents without sufficient trials?
     
  4. truth and justice

    truth and justice Well-Known Member

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    What has that got to do with me informing you that once you are on a ventilator then it's too late to give the drug even if it did work. Are you still saying give it to them anyway because they only have 20% of surviving? And why have you mentioned NYC? It's the same rate worldwide. It seems that you don't even know how the drug is supposed to work
     
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  5. Bowerbird

    Bowerbird Well-Known Member

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    Oh! Please inform me about the differential diagnosis especially since this is at present medical conjecture relating to ARDS

    Please tell me about EBP since you seem to know all about it and do please list the sites most commonly referenced by medical staff

    No supporting evidence?

    I have a whole thread of supporting evidence

    BTW please read my signature so that if I no longer reply to you you know why

    Playing “gotcha” is simply trolling
     
    Last edited: Apr 15, 2020
  6. Bowerbird

    Bowerbird Well-Known Member

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    And others have shown more promise
     
  7. Bowerbird

    Bowerbird Well-Known Member

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    When you find actual evidence of same please post it

    And thanks for insulting the entire medical profession who are doing their best and putting thier lives on the line so that people can go online and blame them for killing patients
     
  8. DivineComedy

    DivineComedy Well-Known Member

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    Irregular heartbeats already listed under warnings for that drug prior to known existence of Corvid-19.
     
  9. Lesh

    Lesh Banned

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    And you would become a vegan...a loud one

    So there's that
     
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  10. Lesh

    Lesh Banned

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    I wouldn't get too excited about some study in Brazil.

    The Mayo Clinic is about half way through an actual double blind trial.

    THAT might be interesting
     
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  11. Bowerbird

    Bowerbird Well-Known Member

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    Yes because it increases the QT interval
     
  12. Lesh

    Lesh Banned

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    I keep rreading about that and haven't been able to get a definition. What is a QT interval?
     
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  13. Bowerbird

    Bowerbird Well-Known Member

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    upload_2020-4-15_21-42-51.jpeg
    Ok this a a layman’s explanation so apologies if I pitch it in simple terms but I want it simple enough for everyone to understand (including the Tr........ err better not go there :p)

    It is this bit of an ECG and it represents the contraction and relaxation of the heart. If it is longer than normal it means that the cardiac cycle is slower

    https://litfl.com/qt-interval-ecg-library/

    The biggest concern is it can easily trigger a dangerous form of irregular heartbeat (torsades de pointes) with low to no blood pressure
    upload_2020-4-15_21-54-15.jpeg
    https://en.ecgpedia.org/wiki/Long_QT_Syndrome

    It actually is not that easy to interpret

    https://jamanetwork.com/journals/jama/fullarticle/1357296

    So it becomes concerning that this issue is being managed by GPs who may not truly understand all the subtleties inherent
     
  14. Lesh

    Lesh Banned

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    Thanks. I understand somewhat now
     
  15. DivineComedy

    DivineComedy Well-Known Member

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    "Heart problems like heart failure and abnormal heartbeats have happened in people taking high doses of chloroquine for a long time. Sometimes, these have been deadly." https://www.drugs.com/cdi/chloroquine.html

    "A small study in Brazil was halted early for safety reasons after coronavirus patients taking a higher dose of chloroquine"

    Seriously, if the drug already warns about high doses, why do that?

    In elderly patients it warns them more. I didn't check my old PDR to see what it said, the drug is old enough to be there though. The doc gave me a drug once and the side effect I had was not in the PDR but was unofficially on the Internet, other people complaining about the same symptoms, doc said it shouldn't do that, stopped taking it, symptom went away.

    You have probably seen commercials on TV for some drug to help a cosmetic condition, something you can live with, but the drug can cause sudden death; it happens, we simply are not all alike.
     
  16. 557

    557 Well-Known Member

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    I have explained all those things in detail in other posts. I’ve quoted your claims and explained your errors. You can put me on ignore if you wish. It will not change the truth. And I will continue to push for the truth on this issue whether you have the constitution to deal with it or not. This is not everyday politics to me. It’s more important than that because lives depend on getting things right.

    I’m not looking up all my explanations to you but I will supply my response to your claim of a list of drugs more promising than chloroquine. Then you are welcome to provide actual evidence to support your claim, not vague links.


     
  17. 557

    557 Well-Known Member

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    I gave you evidence when you made the claim C19 ARDS was the same as traditional ARDS. I’ll look it up and include our exchange below. You continue to make claims in these C19 threads that are verifiably untrue, you are shown your error, and we hear nothing until you make another untrue, unsubstantiated claim. I really do think this issue is too important to approach in that manner.

    If I’ve insulted the medical profession by pointing out the errors and lack of data for ventilator use, you have by all your untrue, unsubstantiated statements. I know it’s frustrating to try and defend ventilator use and denigrate chloroquine use using the same logic. That’s my point. We can’t defend one thing without hard, published data and criticize something else for not having the same.

    To be clear, my statements on ventilators is not a criticism. It’s only to demonstrate inconsistencies in your approach. Many of my friends work in healthcare and I have the utmost respect for them.


     
  18. mitchscove

    mitchscove Well-Known Member Donor

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    Trump never told Democrats to eat fish tank cleaner as he was accused of and he mentioned hydroxchloroquine, not chloroquine, the former being a safer, more effective rendition. Use is being ramped up all over the world because few are willing to let people die to prove a point like our Democrats. Hydroxchloroquineis not a panacea, but it has helped some people and reportedly doctors treating COVID patients have taken it and haven't gotten ill.
     
  19. jay runner

    jay runner Banned

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    You probably have as good a chance by ingesting Quaker buttons as you do by going on a ventilator. For some reason the death rate on ventilators is a little worse in NYC than elsewhere, maybe because of the heavy workload, but ventilator results were piss poor everywhere even before the corona pandemic:

    https://www.sacbee.com/news/coronavirus/article241893476.html

    "Amid a global ventilator shortage during the coronavirus pandemic, some doctors are trying to find other ways to treat patients due to the high percentage of people who die while on ventilators, media outlets reported.

    Typically, 40 to 50 percent of patients with severe respiratory illness (other than COVID-19) will die on ventilators, the Associated Press reported. Yet so far, in New York City, 80 percent or more of the COVID-19 patients put on ventilators have died. And a small study of the patients on ventilators in Wuhan found that 86 percent had died. Numbers out of the U.K. are slightly more promising, with 66 percent dying."

    Ventilators are the most sure means to hell and death.
     
  20. StillBlue

    StillBlue Well-Known Member

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    Apparently to be effective it requires higher than normal doses.
    Legit studies will come out with when it is indicated to be used and in what dosages if at all. Prior to that it's your doctor guessing. The patients the French doctor treated had a no higher survival rate than without. His contention is that they got better faster. Is that grounds to take the risk of unknown side effects from the higher dosages? We do know that heart attacks and hallucinations are real possibilities.
     
  21. StillBlue

    StillBlue Well-Known Member

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    If you are at the point of needing a ventilator then not having one is a sure means of death and I'm not talking 60 or 80%
     
  22. jay runner

    jay runner Banned

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    The odds against you on a ventilator are so bad that you should try just about anything before going on a ventilator.
     
  23. StillBlue

    StillBlue Well-Known Member

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    The H and A treatment only shows any signs of effectiveness and the anecdotally at that if administered immediately after diagnosis. It then may accelerate you return to health. If you get to ventilator time and you choose other treatments then you will die. Not might die you will die.
     
  24. jay runner

    jay runner Banned

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    There's a sky high chance you will die on the ventilator. Take plasma antibodies, the hydroxychloroquine cocktail, Ivermectin, anything you can beg for and be lucky enough to get first.
     
  25. DivineComedy

    DivineComedy Well-Known Member

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    Not for me. I'm just going to try not to get it, if I do there will probably be too motorcycles in good condition going up for sale cheap, because I'm going to DIE if I get it.
    Getting better faster may be good for some people, maybe less scaring, or whatever, I don't know, but most old people may already be taking drugs for their heart and wouldn't be prescribed that drug anyway.
     
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