Brain salad surgery

waltky · Sep 29, 2016

New Study: After a Stroke, Time is of the Essence...

After a Stroke, Time is Critical, Even More Than Previously Thought
September 28, 2016 | WASHINGTON After a large vessel stroke, a new study finds that a shorter time to treatment after a stroke is critical to having the best recovery.

Stroke is the second leading cause of death worldwide and the third leading cause of disability according to the World Health Organization. Researchers from the University of California, Los Angeles, wanted to find out what window of time could provide the best recovery rate for stroke patients, along with which treatment also worked best. So they reviewed outcomes of more than 1,200 patients experiencing acute ischemic stroke a stoke in a major artery that cuts off the blood supply to the brain. Some patients received standard clot-breaking medicine and others received that plus a thrombectomy, a procedure using a tool that pulls clots out of an artery.

Their findings: the sooner the patient had a thrombectomy, the better the overall recovery. "Time makes a big difference. Every four minutes that goes by after a patient gets to the hospital, one fewer out of 100 patients has a good outcome if the artery hasnt been opened, says Dr. Jeffrey Saver, director of the Comprehensive Stroke Center at the University of California Los Angeles, also known as UCLA.

New Study: After a Stroke, Time is of the Essence

Blood clots in major arteries cause blood to stop flowing to the brain, and without a blood supply, the brain cells begin to die, which is why time is of the essence when treating a stroke. If you get the artery open at three hours, then 65 percent of patients will be able to live independently three months later. If it takes eight hours to get it open, then only 45 percent will be able to live independently. It makes a major difference in outcome, said Saver.

Saver said it is critical for everyone to know the signs of stroke facial drooping, arm weakness and difficulty with speech. When these symptoms appear, it's critical to get emergency care. "Often the patient can't make the call themselves because the stroke is affecting their speaking or their ability to recognize they are having a stroke," he said. The study was published in JAMA, The Journal of the American Medical Association. Some researchers say the study may change the treatment stroke patients receive when they first come into the hospital.

http://www.voanews.com/a/stroke-time-critical/3528260.html
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waltky · Jan 10, 2017

Granny says dat's why people lived to ripe old ages inna Biblical times...

Chemical Extracts from Mediterranean Plants May Help Brain Diseases
January 09, 2017 | WASHINGTON Extracts from plants found in abundance in and around the Mediterranean eventually may be used to help treat people with Alzheimer's and Parkinson's disease.

Scientists said chemicals in prickly pear and brown seaweed appear to interfere with the formation of sticky plaques found in the brains of those suffering from the two neurodegenerative, age-related diseases. The plaques are a hallmark of both Alzheimer's and Parkinson's that lead to a gradual reduction in brain function and to death.

Prickly pears are displayed for sale at a stall in Beirut, Lebanon, July 22, 2014. A dozen prickly pears are sold for approximately $4 in the Lebanese market.

The extracts, said researchers, appeared to replace the harmful sticky clumps with deposits that were less toxic. Researchers at the University of Malta and the National Center of Scientific Research at the University of Bordeaux tested the plants' chemical extracts on Brewer's yeast with beta amyloid deposits, similar to those seen in Alzheimer's disease.

Study done using fruit flies

Scientists said the yeast's health improved dramatically after exposure to the chemicals. They next tested the extracts in fruit flies that were genetically modified to develop symptoms of Alzheimer's. When the flies were given brown seaweed extract, their lifespans increased by two days, according to investigators. Prickly pear prolonged the insects' lives by four days. Researchers said one day in the life of a fruit fly is the equivalent to a human year. Significantly, improvement was noted in the movement of some of the diseased insects.

Gummy protein overload

In a fly model of Parkinson's disease, scientists discovered the extracts also extended the lifespan of flies whose brains were overloaded with a gummy protein implicated in Parkinson's disease called alpha-synuclein. The research was reported in the journal Neuroscience Letters. Researchers said it appears the same biological pathways in the brain lead to the formation of sticky plaques seen in both diseases. They added that targeting those pathways is the most promising avenue in the fight against the neurodegenerative diseases.

Extracts are very safe

Lead author Ruben Cauchi of the University of Malta's Center for Molecular Medicine and Biobanking said the Mediterranean plant extracts already are on the market in health foods and some cosmetics, making them very safe. The research team is working with a company that extracts the chemicals for commercial use as fountain of youth preparations.

http://www.voanews.com/a/alzheimers-parkinsons-patients-helped-by-plant-extracts/3669879.html
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waltky · Apr 7, 2018

People as old as 79 could still generate new brain cells...

New brain cells in the old? Study stokes debate
Sat, Apr 07, 2018 - MEMORY: After a study last month found no evidence of new neurons past the age of 13, a study this month reported ‘equivalent volumes of the hippocampus across ages’

People as old as 79 could still generate new brain cells, researchers said on Thursday, stoking fresh debate among scientists over what happens to our brains when we age. The report by scientists at Columbia University in New York, published in the journal Cell Stem Cell, runs directly counter to a study published in Nature last month that found no evidence of new neurons being created past the age of 13. While neither study is seen as providing the definitive last word, the research is being closely watched as the world’s population ages and scientists seek to better understand how the brain ages, for clues to ward off dementia. The focal point of the research is the hippocampus, the brain’s center for learning and memory. Specifically, researchers are looking for the foundations of new brain cells, including progenitor cells, or stem cells that would eventually become neurons.

Using autopsied brain samples from 28 people who died suddenly between the ages of 14 and 79, researchers looked at “newly formed neurons and the state of blood vessels within the entire human hippocampus soon after death,” the Cell Stem Cell study said. “We found that older people have similar ability to make thousands of hippocampal new neurons from progenitor cells as younger people do,” said lead author Maura Boldrini, associate professor of neurobiology at Columbia University. “We also found equivalent volumes of the hippocampus across ages,” Boldrini said. The findings suggest that many seniors could retain more of their cognitive and emotional abilities longer than previously believed. However, Boldrini said these new neurons might be less adept at making new connections in older people, due to aging blood vessels.

Animals such as mice and monkeys tend to lose the ability to generate new brain cells in the hippocampus with age. Just how the human brain reacts to aging has been controversial, although the widely held view is that the human brain does continue to generate neurons into adulthood, and that this “neurogenesis” could one day help scientists tackle age-related brain degeneration. However, a study last month led by Arturo Alvarez-Buylla of the University of California in San Francisco found the opposite. Looking at brain samples from 59 adults and children, “we found no evidence of young neurons or the dividing progenitors of new neurons” in the hippocampi of people older than 18, he told reporters when the study was published. They did find some in children between birth and one year, “and a few at seven and 13 years of age,” he said.

That study was described by experts as “sobering,” because it indicated that the human hippocampus is largely generated during fetal brain development. Alvarez-Buylla’s lab responded to the latest research in a statement saying that they were unconvinced Columbia University had found conclusive evidence of adult neurogenesis. “Based on the representative images they present, the cells that they call new neurons in the adult hippocampus are very different in shape and appearance from what would be considered a young neuron in other species, or what we have observed in humans in young children,” they said. Boldrini, for her part, said her team used flash-frozen brain samples, while the California researchers used samples that were chemically preserved in a process that might have obscured the detection of new neurons.

http://www.taipeitimes.com/News/world/archives/2018/04/07/2003690873
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DoctorWho · Apr 8, 2018

I am Sofa King We Todd it wasting time reading Medical Topics by Non Medical Personnel.
No more from now on.

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