Ebola virus

Selivan · Aug 3, 2016

African
Mortality% = 90

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America and Europe has no vaccine ...

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Russia has created a vaccine

HonestJoe · Aug 3, 2016

Your statement is fundamentally false; https://en.wikipedia.org/wiki/Ebola_vaccine#Vaccines_in_development_and_in_use

I also consider it highly distasteful to play such a nationalist angle on an issue like this. I’d hope and expect most of the people working on these various potential vaccines, wherever they’re based and whoever they’re working for, would see success as humans having a vaccine, not just Russia, the US or Europe.

waltky · May 16, 2017

Ebola reappears in the Congo...

Congo Faces New Ebola Outbreak
May 13, 2017 - The World Health Organization says the Democratic Republic of the Congo is again facing an outbreak of the contagious and deadly Ebola virus.

Congolese Health Minister Oly Ilunga announced Saturday that three people had died of the virus in the northeast of the country. Ilunga urged people not to panic and said officials had taken all necessary measures to respond to the outbreak. The World Health Organization said it was working with Congolese authorities to deploy health workers in the remote area where the three deaths occurred, all on April 22. Eleven other cases are suspected in the area.

This undated colorized transmission of an electron micrograph file image made available by the U.S. Centers for Disease Control and Prevention shows an Ebola virus virion. Health authorities are investigating suspected cases of Ebola in a remote northeastern part of the Democratic Republic of the Congo.

WHO's regional director for Africa, Matshidiso Moeti, went to the Congolese capital, Kinshasa, on Friday to discuss disease response. The remoteness of the affected area, 1,300 kilometers from Kinshasa, means word of the outbreak was slow to emerge. WHO said specialist teams were expected to arrive in the area, known as the Likati health zone, within the next day or two. This was the first outbreak of the virus in DRC since 2014, when 49 people died of Ebola.

Larger outbreak

Experts say the 2014 DRC outbreak was not linked to a much larger outbreak that killed 11,000 people in Guinea, Sierra Leone and Liberia, beginning in 2013. They say active virus transmission for that outbreak was halted last year. In December 2016, The Lancet, a medical journal, published results of a WHO-led trial showing that the world's first Ebola vaccine provides substantial protection against the virus. Among more than 11,000 people who were vaccinated in the trial, no cases of Ebola virus disease occurred. Reports say the vaccine is now awaiting formal licensing clearance.

Ebola, named for the Congolese river near where it was first identified in 1976, begins with a sudden fever, aching muscles, diarrhea and vomiting. It is a hemorrhagic fever, marked by spontaneous bleeding from internal organs and, in most cases, death. It can be transmitted by close contact with infected animals or people, usually through blood or other bodily fluids. People can contract the virus through direct contact with victims' bodies at funerals. Caretakers, nurses and doctors treating Ebola patients also are at high risk.

http://www.voanews.com/a/congo-faces-new-ebola-outbreak/3850841.html
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WHO Confirms Second Ebola Case in Congo Outbreak
May 14, 2017 - The World Health Organization (WHO) confirmed on Sunday a second case of Ebola in Democratic Republic of Congo after an outbreak this week of 17 other suspected cases.

Health officials are trying to trace 125 people thought to be linked to the cases identified in the remote northeastern province of Bas-Uele province in northeastern Congo near the border with Central African Republic, WHO's Congo spokesman Eugene Kabambi said. Three people have so far died among the 19 suspected and confirmed cases, he added.

A health worker sprays a colleague with disinfectant during a training session for Congolese health workers to deal with Ebola virus in Kinshasa

It was not immediately clear how the first victim, a deceased male, caught the virus, although past outbreaks have been linked to contact with infected bush meat such as apes. The outbreak comes just a year after the end of an epidemic in West Africa killed more than 11,300 people mostly in Guinea, Sierra Leone and Liberia.

However, Congo, whose dense forests contain the River Ebola near where the disease was first detected in 1976, has experienced many outbreaks and has mostly succeeded in containing them without large-scale loss of life. The GAVI global vaccine alliance said on Friday some 300,000 emergency doses of an Ebola vaccine developed by Merck could be available in case of a large-scale outbreak and that it stood ready to support the Congo government on the matter.

http://www.voanews.com/a/who-confirms-second-ebola-case-democratic-republic-congo/3851357.html
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Related:

Study: Most Effective Measures Identified for Containing Ebola
May 15, 2017 | WASHINGTON — A small outbreak of Ebola virus in Democratic Republic of the Congo is causing alarm among public health officials. A new study outlining containment strategies may help prevent an epidemic similar to the one that engulfed a number of western African countries two years ago.

In the timely report, published in the journal Proceedings of the National Academy of Sciences, an international team of researchers culled 37 studies for the most effective containment strategies. Pennsylvania State University biology professor Katriona Shea, co-author of the study, said, "The best strategy that we found out of the five that we looked at were funeral containment and public information campaigns [for the] sort of care in the community."

People pass a banner reading "Stop Ebola," forming part of Sierra Leone's Ebola-free campaign in the city of Freetown, Sierra Leone

Ebola virus is spread through coming into contact with the bodily fluids of infected individuals. Shea said investigators found the No. 1 way to prevent transmission was for loved ones to avoid washing bodies of the deceased prior to burial. Shea said that information is best conveyed through public health campaigns that also stress the importance of handwashing, personal hygiene and self-quarantine in high-transmission areas.

Don't wait to get treatment

People suspected of being infected with Ebola, the report found, should also not hesitate to go to the hospital or clinic for evaluation and treatment. But researchers concluded building more hospitals in response to an epidemic to be the least effective way to prevent spread of Ebola within communities. Shea said investigators undertook the study in response to the Ebola epidemic of 2014-2015, when 28,646 people became infected. Of these, 11,323 people died in Guinea, Liberia and Sierra Leone died as of March 2016, according to the report.

The Ebola virus treatment center in Paynesville, Liberia

Forty cases of the disease were also reported in the DRC. Using the prevention strategies outlined in the study and the incidence data from the epidemic, researchers estimated that there would have been a reduction of 3,266 cases of Ebola and 1,633 lives saved.

No consensus on containment

At the height of the epidemic, Shea said there was no consensus on the best ways to contain the Ebola epidemic, and that's why researchers decided to look into the matter. "We really wanted to try to do something. Many of us have children, and were moved by stories, individual horrors and so forth," she said. "Others of us felt something we did scientifically might contribute to making the future outbreaks less horrific."

There are now three confirmed Ebola deaths in a remote part of the DRC. Public health officials are reportedly investigating a total of nine suspicious cases of the deadly viral infection. With the virus once again threatening to become a public health menace, Shea said it's not too early to begin taking aggressive measures to prevent another Ebola epidemic.

http://www.voanews.com/a/most-effective-measures-identilfied-for-containing-ebola/3852382.html
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waltky · May 20, 2017

Possible cure for all five known Ebola viruses discovered...

Scientists Discover Human Antibodies to Fight Ebola Virus
May 18, 2017 - Scientists have discovered a possible cure for all five known Ebola viruses, one of which ravaged West Africa in recent years.

The so-called broadly neutralizing antibodies were discovered in the blood of a survivor of the West African epidemic, which ran from late 2013 to mid-2016. The deadly virus killed more than 11,000 people of the nearly 29,000 who became infected in Liberia, Guinea and Sierra Leone. Ebola got its name from the first documented outbreak, which occurred along the Ebola River in the Democratic Republic of the Congo, formerly Zaire, in 1976. Since then, there have been two dozen outbreaks of Ebola in Africa, including a current one that has infected nine people in the DRC. Three people have died.

A health worker takes the temperature of people to see whether they might be infected by the Ebola virus inside the Ignace Deen government hospital in Conakry, Guinea

Kartik Chandran, a professor in the Department of Microbiology and Immunology at the Albert Einstein College of Medicine in Bronx, New York, helped identify the antibodies, which were described online in the journal Cell. He is optimistic that the antibodies can be used as a single therapy to treat all Ebola viruses. "Based on the nonhuman primate studies that are ongoing, and given the fact that they are pretty predictive, I would be optimistic that they could be used to protect people and reverse disease," Chandran said.

350 antibodies isolated

Researchers isolated about 350 antibodies from the human blood sample, two of which showed promise in neutralizing three viruses in tissue culture. The antibodies work by interfering with a process that the pathogen uses to infect and multiply inside cells. The drug company Mapp Pharmaceutical Inc. is now testing the antibodies in monkeys to make sure they are safe and effective. A forerunner of the experimental drug, called Zmapp, was in the experimental stages when it was pressed into service during the last epidemic. Zmapp is a combination of cloned antibodies discovered in mice that enlist the body's natural immune system to fight infection. If given up to five days after symptoms appear, it can cure the disease.

The problem, Chandran said, is Zmapp is not terribly specific and works to neutralize only Ebola Zaire, one of the five known viruses. He said the broadly neutralizing human antibodies attack and destroy all of the viruses. It took scientists just six months to discover the antibodies, according to Chandran, "so this is really incredibly fast and incredibly gratifying. And we are hoping that things will continue at this pace and that in very short order we will be in a position to be able to test these things in people." While the broadly neutralizing antibodies are being developed as a treatment, Chandran envisions using them in a vaccine that can be given ahead of an Ebola outbreak to guard against infection.

http://www.voanews.com/a/scientists-discover-human-antibodies-fight-ebola-virus/3860494.html
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Skruddgemire · May 23, 2017

Selivan said: ↑

African
Mortality% = 90

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America and Europe has no vaccine ...

=========================
Russia has created a vaccine

Click to expand...

Sorry, as much as Chekov might want to claim that it "was inwented by a little old woman in Lenningrad", the first 70%-100% Effective vaccine that is currently undergoing trials was invented by the Canadians.

waltky · May 25, 2017

So. Sudan partially closes border due to ebola scare...

South Sudan State Partially Closes Border in Ebola Scare
May 23, 2017 - State authorities in South Sudan closed part of their border with the Democratic Republic of the Congo last week in an effort to prevent the spread of the deadly Ebola outbreak, declared by the World Health Organization in a remote, northern part of the DRC two weeks ago.

The WHO has confirmed that four people have died from the disease in the DRC. Lino Utu, deputy governor of Tambura state, said the movement of people and goods between the two countries at the border town of Ezo had been restricted until further notice. "We closed the border temporarily because of Ebola," Utu said. "We have been told it has been found in DR-Congo. If we leave the border open, it can trickle down to Tambura state." He said the area along the border with the DRC had been teeming with activity, "because it is where the people from the Democratic Republic of the Congo bring in their goods, and also the people from Tambura state bring in their goods. It's a big market."

A health worker sprays a colleague with disinfectant during a training session for Congolese health workers to deal with Ebola virus in Kinshasa

Uto said doctors have confirmed that Ebola can be found in bushmeat, so state officials have temporarily banned the sale of all bushmeat in the markets. "We cannot allow bushmeat to be sold any longer because people can easily contract Ebola from meat," Utu said. The minister of health was informed about Tambura's move to close the border at Ezo on Tuesday. Utu said international health workers, including those with the WHO, are partnering with local officials to educate the public about how Ebola is spread. "This is awareness that has been going on and on and on," he added. Utu is appealing to the WHO to send experts to Tambura to screen people for the deadly virus "and advise us in other areas as far as how Ebola is contracted and how we can prevent the spread of Ebola," he said, adding, "I really need them to come to us on the ground in Tambura state."

A woman sells monkey meat in a market in Kisangani, Democratic Republic of Congo

Authorities in Gbudue state, which also runs along the DRC, have banned the sale of bushmeat in Yambio markets, but have kept border crossing points open. The Gbudue state minister for information, Gibson Bullen Wande, said wildlife officials are creating awareness about the dangers of eating bushmeat. He said state officials and nongovernmental organization health partners have trained and deployed health workers along the border to monitor movement of traders. "We have also left some medical workers along those areas to let them monitor," he said. Bullen said as far as he is concerned, it is the responsibility of the national government to decide whether to close the border between the two countries. On Tuesday, the state director of wildlife went on the air to warn people against eating bushmeat. "We are going to ban the sale of all bushmeat or any trading of the bushmeat [because] those are the things that people get Ebola from," Bullen said.

http://www.voanews.com/a/ebola-south-sudan-partially-closes-border/3867797.html
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waltky · May 29, 2017

Congo to Use Ebola Vaccination to Fight Outbreak...

Congo Approves Use of Ebola Vaccination to Fight Outbreak
May 29, 2017 — Democratic Republic of Congo's Health Ministry has approved the use of a new Ebola vaccine to counter an outbreak of the hemorrhagic fever in its northeast that has killed four people, a spokesman said on Monday.

"The non-objection was given. Now there's a Medecins Sans Frontieres team that is arriving [in Congo] today to validate the protocol with the technical teams," Jonathan Simba, a Health Ministry spokesman, said by telephone. The vaccine, known as rVSV-ZEBOV and developed by Merck, is not yet licensed but was shown to be highly protective against Ebola in clinical trials published last December.

A health worker injects a woman with an Ebola vaccine during a trial in Monrovia
As of Friday, Congo had registered 52 total suspected cases, including two that have been confirmed, the World Health Organization spokesman in Congo, Eugene Kabambi, said by telephone, adding that the situation appears to be under control.

Simba said that the details of the vaccination campaign would be announced after a meeting of the health ministry and its partners set to take place on Monday or Tuesday. A vaccination campaign would present logistical challenges in Congo's isolated northeastern forests, including transporting and storing the vaccine in special containers at the required minus 80 degrees Celsius.

http://www.voanews.com/a/congo-ebola-vaccination/3875328.html
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Genetic Testing Underway on Virus Behind New Ebola Outbreak
May 26, 2017 - Tests are underway to determine the genetic sequence of the Ebola virus behind an outbreak in central Africa, a U.S. Centers for Disease Control researcher said Friday.

Dr. Barbara Knust, an epidemiologist, told VOA's Horn of Africa service that scientists are looking for "clues" about where this strain of Ebola originated and how to treat it. "That could help [us] understand how this virus is related to other viruses that have caused other Ebola outbreaks," she said.

The latest Ebola outbreak is in northern Democratic Republic of the Congo, in a remote area near the border with the Central African Republic. The World Health Organization said that as of May 24, Ebola had killed four people in the area and the number of suspected cases stood at 44. The Ebola virus, which causes a type of hemorrhagic fever, killed more than 11,000 people across the West African countries of Guinea, Liberia and Sierra Leone in 2014 and 2015.

Health workers wash their hands after taking a blood specimen from a child to test for the Ebola virus in a area were a 17-year old boy died from the virus on the outskirts of Monrovia, Liberia
Resources 'mobilized quickly'

Staff from the CDC, the WHO, the Congolese Ministry of Health and other agencies are in Congo's Bas Uele province, working to contain the spread of the virus. Knust said the international response was going "fine." "The responders involved in this outbreak very certainly are taking it seriously and the resources have been mobilized quickly," she said. "At least at this point of time [it] appears that it was detected fairly early, although that information is forthcoming. There is some hope it will remain a limited outbreak." She said there had been discussion of using experimental treatments used in the West African outbreak, but that the Congolese government had not given its approval.

Dr. Galma Guyo, a disease control specialist in Nairobi, was part of an African Union team that responded to the Ebola outbreak in Liberia. He warned that the DRC's location in the center of Africa could allow the virus there to spread across borders. "There is a possibility that the viruses can easily spread and be hard to detect due to the remoteness of the region, too," he said.

http://www.voanews.com/a/genetic-testing-underway-virus-ebola-outbreak/3873011.html
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yiostheoy · May 29, 2017

The W.H.O. is saying mortality is around 50%.

This is not hard to google. I did it in less than 1 min.

http://www.who.int/mediacentre/factsheets/fs103/en/

waltky · May 8, 2018

Ebola outbreak in Congo...

Seventeen deaths reported in Congo as Ebola outbreak confirmed
May 8, 2018 - At least 17 people have died in an area of northwestern Democratic Republic of Congo where health officials have now confirmed an outbreak of Ebola, the health ministry said on Tuesday.

It is the ninth time Ebola has been recorded in the central African nation, whose eastern Ebola river gave the deadly virus its name when it was discovered there in the 1970s, and comes less than a year after its last outbreak which killed eight people.

“Our country is facing another epidemic of the Ebola virus, which constitutes an international public health emergency,” the ministry said in a statement.

“We still dispose of the well trained human resources that were able to rapidly control previous epidemics,” it said.

https://www.reuters.com/article/us-...ngo-as-ebola-outbreak-confirmed-idUSKBN1I91VS
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waltky · May 14, 2018

Congo Approves Use of Experimental Ebola Vaccine...

WHO: Congo Approves Use of Experimental Ebola Vaccine
May 14, 2018 — Congo has agreed to allow the World Health Organization to use an experimental Ebola vaccine to combat an outbreak announced last week, the WHO director-general said Monday.

The aim is for health officials to start using the vaccine, once it's shipped, by the end of the week, or next week if there are difficulties, said WHO Director-General Tedros Adhanom Ghebreyesus. “We have agreement, registration, plus import permit — everything formally agreed already. And as you know that vaccine is safe and efficacious and has been already tested. So I think we can all be prepared,” he said. “All is ready now, to use it.” The outbreak was announced last week in Bikoro, in Congo's northwest. Health officials traveled there after Congo's Equateur provincial health ministry on May 3 alerted them to 17 deaths from a hemorrhagic fever. As of May 13, Congo has 39 suspected, probable and confirmed cases of Ebola since April, including 19 deaths, WHO reported. Two cases of Ebola have been confirmed.

Congo's Ministry of Health has requested that WHO send 4,000 doses of the vaccine, said ministry spokeswoman Jessyca Ilunga, who said they should arrive by the end of the week. “The vaccination campaign starts next week, everything depends on the logistics because the vaccine must be kept at minus 60 degrees Celsius, and we need to assure that the cold chain is assured from Geneva to Bikoro,” she said. The Ebola vaccination campaign will first target health workers, Ilunga said. Three nurses are among those with suspected cases, and another is among the dead. The teams on site have already identified more than 350 contacts, who are people who have had contact with the patients, she said.

A health worker is sprayed with chlorine after visiting the isolation ward at Bikoro hospital, which received a new suspected Ebola case, in Bikoro, Democratic Republic of Congo

Mobile laboratories were deployed to Mbandaka and Bikoro on Saturday, she said, adding that results from the first 12 samples tested with that method should be available tomorrow. This is the ninth Ebola outbreak in Congo since 1976, when the deadly disease was first identified. Congo has a long track record with Ebola, WHO said. The last outbreak that was announced a year ago, was contained and declared over by July 2017. None of these outbreaks was connected to the massive outbreak in Guinea, Liberia and Sierra Leone that began in 2014 and left more than 11,300 dead. There is no specific treatment for Ebola, which is spread through the bodily fluids of people exhibiting symptoms. The new experimental vaccine, developed by the Canadian government and now licensed to the U.S.-based Merck and has been shown to be highly effective against the virus. It was tested in Guinea in 2015.

Though the Congo outbreak is of a different strain, the experimental vaccine is still thought to be safe and effective. WHO chief Tedros had led a delegation to the affected region on Sunday. The Bikoro health zone is about 150 kilometers (93 miles) from Mbandaka, the capital of the Equateur province, and 45 kilometers (28 miles) from Ikoko Impenge, where there are other suspected cases. WHO is working with Congo's government and other international organizations, including Medecins Sans Frontieres (Doctors Without Borders), to strengthen coordination to fight and contain the Ebola outbreak.

https://www.voanews.com/a/who-congo-approves-use-of-experimental-ebola-vaccine/4393433.html
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waltky · Jul 30, 2018

Bats now carry ebola...

New Ebola species is reported for first time in a decade
Jul 28, 2018 - The family of Ebola viruses has just gotten a bit bigger.[/i]

The government of Sierra Leone has announced that a new species of Ebola, the sixth, has been discovered there in bats. It has been called, provisionally, the Bombali virus, after a district in the north of the country where it was found. There’s no evidence the new virus has infected people, although EcoHealth Alliance, an environmental nonprofit group involved in the discovery, said on Twitter that it has the potential to infect human cells. The discovery was made by scientists from the University of California at Davis and Columbia University as part of a U.S.-funded effort to find unknown viruses that have the potential to cause outbreaks in people. “It is really interesting. I think it’s exciting. But I think we have a lot of work to do to really understand if it is a pathogen and whether it does or doesn’t pose a threat,” Tracey Goldstein, of the One Health Institute at UC Davis, told STAT on Friday.

Peter Daszak, CEO of EcoHealth Alliance, said a scientific paper detailing the discovery is in the publication pipeline. Some journal forbid public discussion of work they are considering publishing and Goldstein would not say anything about where and when the work would be published. The normal process for announcing the discovery of a new virus is through a peer-reviewed journal, where the scientists making the claim lay out details of how they found the virus — or in this case, genetic evidence of a virus — and the work they did to prove that it was new, and not simply a new strain of an already known pathogen. However, Sierra Leone, which had been notified of the discovery, wanted to first make the announcement to local press on Thursday. “They want to preempt negative rumors, and are rolling out education programs to reduce potential for spillover,” Daszak said.

Doctors help each other with their protective suits during an Ebola virus drill at the Doctor Ramon de Lara hospital in the Dominican Air Force base at Santo Domingo

Goldstein said the virus was discovered in two types of bats of the Molossid family, Angolan free-tailed bats and Little free-tailed bats. These two species of bats roost together, Goldstein said. They are found widely across sub-Saharan Africa. The infected bats were found roosting in people’s homes, she reported in ProMED, an online infectious disease reporting system. The scientists did not try to extract live viruses from samples taken from the bats, Goldstein said. Viral fragments – RNA – were detected; there was enough material to sequence “an almost complete genome,” Daszak said. The Centers for Disease Control and Prevention have received samples from bats that tested positive for the Bombali virus.

Stuart Nichol, chief of the viral special pathogens branch, said the CDC scientists will try to see if they can extract a whole infectious virus from oral and rectal swabs taken from the bats. Nichol said it’s clear from the genetic sequence of the Bombali virus that it is sufficiently different from other types of ebolaviruses to qualify as a separate species. Whether the virus is dangerous to humans isn’t currently known. The scientists who discovered it made a copy of the main protein on the exterior of the virus — using the genetic code as the recipe, Nichol said. They put that protein on what’s called a pseudovirus, a benign synthetic virus-like entity that is used in research. The pseudovirus bearing the Bombali virus protein was able to infect human cells, he said. But you cannot conclude from that that the Bombali virus would sicken people. “Just because it enters human cells doesn’t mean it will cause human disease,” Nichol said.

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Moi621 · Jul 30, 2018

I'm okay with it except when they fly infected people
over the natural oceanic containment barrier to

How stupid is that.
How disrespectful to the Public Health.

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Ebola virus

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