Largest peanut allergy study points to life-saving treatment

Discussion in 'Health Care' started by Bluesguy, Nov 19, 2018.

  1. Bluesguy

    Bluesguy Well-Known Member Donor

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    This is good news but puzzling because slow exposure to an allergen has been used for decades. Peanuts are an excellent source of protein especially for kids going to school as they do not require refrigeration and can be combined with lots of different things. When it was first developed during hard times and people could not afford meat peanut butter was the leading source of protein. When I was in school back in the days peanut butter sandwiches, peanut butter crackers, peanut candy was a mainstay and I don't recall any other kids having issues with them. Used to be the main snack on airplane flights. So hopefully they will further use these techniques so the vast majority of kids are not deprived of such a valuable source of nutrition.

    Largest peanut allergy study points to life-saving treatment

    Peanut allergy sufferers have been given new hope following the results of the largest study of its kind in the world.

    Children diagnosed with a severe allergy took part in a trial where they were given increasing amounts of peanut protein over a year.

    The landmark trial found that participants not normally able to tolerate exposure to even a tenth of a single peanut could eventually cope with two whole peanuts.

    It is believed that by gradually building up tolerance levels, allergy sufferers could protect themselves from accidental exposure.

    Researchers from Evelina London Children's Hospital and King's College London took part in a study which suggests immunotherapy treatment, already used to treat pollen and bee sting allergies, could protect people from life-threatening reactions.

    The PALISADE study recruited nearly 500 children aged four to 17 from the US and Europe to take part in the largest-ever peanut allergy treatment trial.

    Participants were split into groups who received either a capsule of peanut protein or a dummy powder.

    Doses were gradually increased every two weeks for a period of six months, before continuing on a "maintenance dose" of peanut for a further six months.

    The results, published in the New England Journal of Medicine, found about two-thirds (67%) of children and teenagers could tolerate at least 600mg of peanut protein, compared with just four per cent of participants on the dummy placebo.


    Professor George du Toit, paediatric allergy consultant at Evelina London and the study's chief investigator, said: "Peanut allergy is extremely difficult to manage for children and their families, as they have to follow a strict peanut-free diet.

    "Families live in fear of accidental exposure as allergic reactions can be very severe, and can even lead to death.

    https://www.telegraph.co.uk/news/20...t-allergy-study-points-live-saving-treatment/
     
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