NIH Has Started Clinical Trials of Hydroxychloroquine

Discussion in 'Current Events' started by XXJefferson#51, May 15, 2020.

  1. XXJefferson#51

    XXJefferson#51 Well-Known Member

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    Source: (AP Photo/John Locher)

    “The National Institutes of Health announced Thursday afternoon government scientists have started clinical trials on hydroxychloroquine, a drug that doctors have successfully used to treat a number of Wuhan coronavirus patients.

    "A clinical trial has begun to evaluate whether the malaria drug hydroxychloroquine, given together with the antibiotic azithromycin, can prevent hospitalization and death from coronavirus disease 2019 (COVID-19). The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is sponsoring the trial, which is being conducted by the NIAID-funded AIDS Clinical Trials Group (ACTG). Teva Pharmaceuticals is donating medications for the study," NIH released Thursday.”






    https://townhall.com/tipsheet/katie...linical-trials-of-hydroxichloroquine-n2568835







    This is good news! Hydroxichloroquine along with azithromycin given early once one is known to have Wuhan virus seems to be effective. Giving it after one is on a ventilator is way too late most of the time. Thanks to Teva Pharmaceuticals of Israel for donating the medication for the study.
     
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  2. XXJefferson#51

    XXJefferson#51 Well-Known Member

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    That people oppose the use of this medication simply because President Trump suggested it may work to reduce the effects of the illness is partisan hate in its most wicked form.
     
  3. HonestJoe

    HonestJoe Well-Known Member Past Donor

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    It would be but did anyone actually oppose ever using this drug just because Trump mentioned it?

    What I recall happening is that lots of people proposed the immediate and widespread use of the drug solely because Trump suggested it might help and they were legitimately challenged on that. Obviously it should be (and has been) studied and tested just like any of the other potential treatments and the fact Trump mentioned that one by name should be irrelevant (and probably shouldn't have happened at all).

    Lots of people spun the entire thing in to a partisan political mess but, as is usually the case, that came from all "sides".
     
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  4. camp_steveo

    camp_steveo Well-Known Member

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    Its been around for decades and is obviously safe. Is it effective is now the question.
     
  5. BaghdadBob

    BaghdadBob Well-Known Member

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    Where's the Zinc Sulfate which is the workhorse of Dr. Zelenko's regimen? HCQ is the gateway & helps the Zinc do its job, and not the other way around.

    Without Zinc the study will not result in a strongly positive outcome ... and they know it ahead of time. They're politicizing peoples' lives. :(

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/
    https://www.researchgate.net/post/Is_a_combo_of_chloroquine_and_Zinc_a_cure_for_coronavirus

    The bio-chemistry is simply explained in this video cut on YouTube:


    Azithromycin aids the Sigma-2 protein receptors from rejecting the virus into the cell. It is, frankly, not a necessity in treatment.

    According to the good doctor if the Zelenko Protocol is administered in the first 5 days with the onset of symptoms there's a 99% chance of no need for hospitalization. The regimen has little to no effect after pneumonia, blood clots, and cytokine storms develop.
     
  6. Hoosier8

    Hoosier8 Well-Known Member Past Donor

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    Over 3,000 patients treated in Raoult's practice and the combo is pretty effective.
     
  7. Jestsayin

    Jestsayin Well-Known Member Past Donor

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    You only need to spend a few minutes searching here to find the answer to your question was totally politically based thinly veiled in the mask of lack of research, followed by dozens. if not hundreds of comments telling us this drug was totally useless and many comments that it would kill you. Many of these comments from posters on other continents or those here who are totally bunkered up and will not leave their homes for fear others are trying to kill them by walking their dog.
    Remdesivir, on the other hand, was touted as the complete opposite by the posters that are heavily left leaning.
     
  8. HonestJoe

    HonestJoe Well-Known Member Past Donor

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    Yes, as I said, a partisan political mess. Nobody came out of it looking good.
     
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  9. Paul7

    Paul7 Well-Known Member

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    Yes.
     
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  10. Paul7

    Paul7 Well-Known Member

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    IOW, a game changer as Trump said.
     
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  11. HonestJoe

    HonestJoe Well-Known Member Past Donor

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    In which case those individuals would be just as stupid as anyone who promoted it solely because Trump mentioned it.

    The fact remains that it shouldn't have involved politics at all. Trump was wrong to call out any one drug by name when he had pretty much zero understanding of what he was actually talking about. If he hadn't made that off-the-cuff statement, the clinical and scientific work with it (and all the other proposed treatments) would have happened pretty much as it did regardless but there would have been much less misinformation and political rhetoric to confuse matters.
     
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  12. jay runner

    jay runner Banned

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    If an extract of skunk shet that was properly filtered and rarefied into a covid pill showed promise and the whole of science was against it, and my choice was try the pill or likely go on a deathalator, I would try the skunk pill.

    Your chances of winning by staying on defense are pretty slim.
     
  13. Paul7

    Paul7 Well-Known Member

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    Trump did nothing wrong, he said it was promising but it may or may not work. Leaders are supposed to give people hope.
     
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  14. HonestJoe

    HonestJoe Well-Known Member Past Donor

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    If it wasn't wrong, why was the only thing it led to even more partisan political hatred and general public confusion? I'm not calling it malicious, just careless.

    I'm all for political leaders making more general statements, like there being lots of promising research in to possible treatments (though also tempering expectations given how early in the process it was at the time). The problem is that he delved in to specific details that he was totally unqualified on and, even if it wasn't his intention or his literal words, he created a false impression of the status of that specific drug at the time.
     
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  15. Paul7

    Paul7 Well-Known Member

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    Because the TDS left has never accepted his election.
     
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  16. jay runner

    jay runner Banned

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    "Sorrento Therapeutics will announce their discovery of the STI-1499 antibody, which the San Diego company said can provide '100% inhibition' of COVID-19, adding that a treatment could be available months before a vaccine hits the market.

    'We want to emphasize there is a cure. There is a solution that works 100 percent,' Dr. Henry Ji, founder and CEO of Sorrento Therapeutics, told Fox News. 'If we have the neutralizing antibody in your body, you don't need the social distancing. You can open up a society without fear.'"

    https://www.foxnews.com/science/cov...rmaceutical-coronavirus-antibody-breakthrough

    I hope this works and that there is no political effort to squash it.
     
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  17. Andrew Jackson

    Andrew Jackson Well-Known Member

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    The Zelenko Protocol is still UNPROVEN.

    making an assertion in a blog post or in a YouTube interview that neither describes the study design nor provides the actual data used to reach a conclusion about efficacy cannot, in any way, be critically evaluated.

    https://www.snopes.com/fact-check/zelenko-669-coronavirus-patients/
     
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  18. Andrew Jackson

    Andrew Jackson Well-Known Member

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    I read the link

    It seems too good to be true.

    But, who knows?

    In any event, their stock price has risen about 90% since the news release.

    Also, IF it really is (as claimed) some sort of "cure", why would there be any "political effort to squash it"?

    Huh? Lolwut?::roflol:

    "Squashing" a potential cure?:smh:
     
    Last edited: May 15, 2020
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  19. vman12

    vman12 Well-Known Member Past Donor

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    They'll also attempt to prove it's "ineffectiveness" by claiming it doesn't work. To do that, they'll eliminate the zinc and azithromycin from the cocktail.

    Watch for those "studies" from the left.
     
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  20. vman12

    vman12 Well-Known Member Past Donor

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    How much is it up from 60 cents a pill?
     
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  21. The Mello Guy

    The Mello Guy Well-Known Member

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    Actually opposition is coming from...oh the trump admin

    A panel of experts convened by the National Institute of Allergy and Infectious Diseases recommends against doctors using a combination of hydroxychloroquine and azithromycin for the treatment of COVID-19 patients because of potential toxicities.
     
  22. vman12

    vman12 Well-Known Member Past Donor

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    Was one of them Dr Notso Bright wearing his little white cloth gloves?

    But sure, we need more clinical trials for a 65 year old drug.

    Next up, tests on the toxicity of penicillin.
     
    Last edited: May 15, 2020
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  23. BaghdadBob

    BaghdadBob Well-Known Member

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    Then I suggest that you, friends, & family members (if you have any) ONLY USED APPROVED therapies for the Wuhan Virus, and nothing else

    For your convenience I'll list all of them here for you ...
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    .
    https://www.cdc.gov/coronavirus/2019-ncov/hcp/therapeutic-options.html
    There are no drugs or other therapeutics presently approved by the U.S. Food and Drug Administration (FDA) to prevent or treat COVID-19.

    Good luck to you & yours! :)
     
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  24. WalterSobchak

    WalterSobchak Well-Known Member

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    Why do Cons care about clinical trials regarding a drug to treat people for a "Liberal Hoax?"
     
  25. Andrew Jackson

    Andrew Jackson Well-Known Member

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    That is a great question, Mr. WS.
     
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