T2 Diabetes is mostly a Voluntary Lifestyle Choice Disease.

Discussion in 'Health Care' started by Bic_Cherry, Mar 5, 2018.

  1. Bic_Cherry

    Bic_Cherry Active Member

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    (Just like Tobacco smoking related Lung Cancer), T2 Diabetes is a Voluntary Lifestyle Choice Disease.


    (Ignorance, Mental-Stress and Ill-discipline are major subsidiary causative factors as well)
    [​IMG]
    1st principles 1st:
    Definition: Diabetes mellitus type 2 is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. https://en.wikipedia.org/wiki/Diabetes_mellitus_type_2

    Blood sugar = calories, aka energy. (https://en.wikipedia.org/wiki/Food_energy)
    Law of conservation of energy:https://en.wikipedia.org/wiki/Conservation_of_energy*energy can neither be created nor destroyed; rather, it can only be transformed from one form to another

    Majority of people with T2 diabetes have a very high % of body fat and a low basal metabolism rate.

    The basal metabolism rate is influenced by the % of skeletal muscle a person has, (obviously, the % muscle to fat is lower in people with a high % body fat). People with a low % muscle have a low basal metabolic rate and are thus more likely to get fat (or are already fat).

    The purpose of Insulin is to help cells absorb glucose in blood (especially fat and liver cells) since brain and muscle cells admit glucose much more readily where necessary (especially when exercising).

    Resistance to Insulin by cells occurs primarily because cellular energy stores (as glucose/ glycogen/ fat) are already full and cannot increase storage any further without bursting or tearing apart the cell wall/ cell architecture. Fat cells have the highest energy storage capacity so usually, insulin resistance happens when fat cells have very low or reduced vacant storage capacity. Just as a bucket filled to the brim with water will overflow upon further influx, diabetes is a condition where the fat cells are filled to capacity and are thus unable to absorb blood glucose (energy) levels further without causing structural damage to themselves. Insulin resistance in this case is thus a product of lassitude and gluttony and not a genetic disease.

    Lifestyle and work also plays a big part since only well trained (/skilled) muscles (and perhaps other cells) can utilise fat as an energy source at high stress/ aerobic intensity (higher VO2 max levels etc). Many cosmopolitan denizens have high stress occupations for which they are physically poorly trained to handle, even should it be a white collar job in nature. Just as a 100m sprint (high VO2max activity in midst of high fight/flight hormone levels) consumes mostly glucose as energy source, a high stress/ toxic work environment results in muscle and other cells preferentially using glucose as energy substrate rather than fat as would be the case in a more tranquil/ harmonious work environment (Insufficient sleep/ rest also causes fight/flight hormone action resulting in higher glucose rather than fat metabolism). Low blood glucose causes hunger pangs and in the context of a hectic work environment, means more binging on fatty foods and sugary drinks to cure hunger pangs quickly as well as alcohol and tobacco products which are all short term stimulants but with long term detriment. Such a lifestyle leads to diabetes at best and a heart attack/ stroke/ cancer in most people which will most likely end their careers and perhaps bankrupt either themselves or their country from the stratospheric healthcare costs of providing care and concern for 40-50 years of ignorance, poor lifestyle choices / ill discipline.

    PS:
    Other consequences of a sedentary lifestyle include:
    Obstructive Sleep Apnoea which contributes to diabetes: poor respiratory muscle tone coupled with a big tummy and fat blocking the respiratory tract causes deep sleep to be interrupted by persistently cycling airway blockage (snoring) when muscles relax and the already partially fat blocked airways become completely blocked/ compressed by fatty tissues (suffocation resulting in repeated subconscious micro awakenings during sleep).

    The poor state of rest results in increased stress hormones (catecholamines) circulating in the blood which in themselves, besides antagonising insulin action, also raise the blood pressure (Hypertension) and shift the energy metabolism choice from fat to glucose: resulting in poor performance (repeated hunger pangs) and even more fat accumulation since high glucose is extremely toxic to blood vessels and especially the kidney: so fat accumulation becomes a one way street, increasing with every meal but not being expanded off in between.

    Diabetes and Hypertension are both partners in crime (mutual accelerants) because they both cause blood vessel inflammation which most likely further increase blood catecholamine levels which both serve to accelerate one another resulting in even more severe (vivious cycle) blood vessel inflammation: both of which are the primary cause of heart attacks, strokes and perhaps even cancer too.

    Ignorance, Mental-Stress and Ill-discipline are thus the primary cause of T2 Diabetes and to be blamed for the stratospheric healthcare costs and high morbidity suffered by modern day society citizens today.

    In conclusion, all people with a high body fat % (and BMI above 18.5) https://www.builtlean.com/2010/08/03/ideal-body-fat-percentage-chart/ need to do more physical exercise and avoid a sedentary lifestyle to improve their skeletal muscle quantity, quality and tone to improve their basal metabolic rate (and personal productivity levels) and thus keep their % body fat below the prescribed levels of 15% for males and 25% for females to avoid the conditions of obesity, diabetes, hypertension, obstructive sleep apnoea, high cholesterol, high mental/ work stress levels etc which place an increasingly unaffordable burden on healthcare costs for all.


    References:
    - [​IMG] https://www.builtlean.com/2010/08/03/ideal-body-fat-percentage-chart/
    - 1 in 3 Singaporeans suffer from sleep apnea: Study: CNA17Mar2016: http://www.channelnewsasia.com/news...poreans-suffer-from-sleep-apnea-study-8137824
    - Start now to prevent and manage chronic diseases: ST27Sept2016: "As of 2010, more than half of Singapore's adult population between 18 and 69 years old have high cholesterol, four in 10 are overweight or obese, a quarter have prediabetes or diabetes and about one in five has hypertension." http://www.straitstimes.com/singapore/health/start-now-to-prevent-and-manage-chronic-diseases
    - 1 in 10 stroke patients here aged under 50: ST, 19Nov2016: "Medical conditions such as high blood pressure or high cholesterol can make a person more likely to get a stroke, say doctors." http://www.straitstimes.com/singapore/1-in-10-stroke-patients-here-aged-under-50

    May not be diabetes, but his symptoms still suggests something wrong with his brain blood flow/blood vessles e.g.: https://en.wikipedia.org/wiki/Transient_ischemic_attack ):
    [​IMG]
     
    Last edited: Mar 5, 2018
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  2. DarkDaimon

    DarkDaimon Well-Known Member

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    So is heart disease, stroke, cancer and many others. So what?
     
  3. Bic_Cherry

    Bic_Cherry Active Member

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    Exercise is telling the cells in your body that U love them, care for them and train them to cope well with daily requirements as well.

    e.g.: Nobody who eats a diet rich in protein will form good skeletal musculature without exercise: the protein just becomes stored as fat which becomes problematic (and even cancer causing) vz hyperglycemia/ DM pathway.

    The following is a proposed pathway:
    Lack of exercise> lack of skeletal musculature (SM)> reduced basal metabolic rate (BMR), increased stress levels due to lack of SM. Clumsiness, poor endurance due to lack of SM and exercise training> obesity due to ,lack of caloric expenditure due to sedentary lifestyle and reduced BMR due to lack of SM building exercise training> increased blood pressure (HBP) due to increased stress due to poor posture, poor work endurance, poor strength, hyperglycemia due to obesity due to low BMR, lack of apoptosis due to lack of exercise signals to all body cells (nerve, muscle, blood vessels etc) unique to exercise related (e.g. sustained increased 70%VO2max activity) to fire off natural cellular renewal and apoptosis pathways> down regulation of immune system due to vascular inflammation from hyperglycemia (diabetes) and inflammatory vascular damage from hypertension. Lack of proper cell differentiation due to lack of exercise signal causing sick cells to fail to undergo apoptosis and mutate into cancer cells. Healthy cells unable to divide because of lack of exercise signal to replicate.

    Vascular damage is what causes stroke and heart disease.
    Improper cell differentiation and failure to set environment favourable for proper cell replication, apoptosis and the handicap of immune system from performing its rightful job of weeding out any rogue cells on the way to becoming cancer cells are what causes uncontrollable cancers eventually.

    The body is an ecosystem. People who neglect their internal ecosystem (usually due to ignorance or ill-discipline: i.e. voluntarily) are those most likely to suffer from vascular and other neoplastic (cancers) diseases.
     
    Last edited: Mar 7, 2018
  4. DarkDaimon

    DarkDaimon Well-Known Member

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    I'm very interested to learn more. Do you have any links?
     
  5. Bic_Cherry

    Bic_Cherry Active Member

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    U can check out latest research reports like https://www.researchgate.net/public...g_Exercise_to_Cancer_Prevention_and_Treatment for the exact/ postulated mechanisms, suffice to say, I believe that exercise is the missing part of the puzzle in the long term prevention of many human lifestyle diseases from heart disease to cancers too but many have not been studied due to corporate lobbying/ lack of government funding since things like exercise will receive very little industry/ commercial funding since it is near impossible for any corporate body to moneytise even the most successful/ promising outcomes since exercise is neither a patentable nor copyrightable commodity.

    PS: many other factors also improve/ worsen cancer risk such as genetic abnormalities, environmental pollution, lifestyles cultures/ habits (smoking, diet, sleep, occupational stress, family relationships) etc. It is the by the sum total of all this causative vs preventive factors that cancers etc result.
     
    Last edited: Mar 11, 2018
  6. Kode

    Kode Well-Known Member

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    I have always watched my diet, have chosen fresh vegetables over canned, avoided HFCS and hydrogenated oil, and have been very active including jogging even now at age 71. And yet at age 66 I became borderline diabetic and take Metformin daily to manage it.

    I think the decline in the pancreas production of insulin is the result of all the pollutants in the environment and our food. Do you realize that a major cancer-causing toxin, perfluoro oxanoic acid, or PFOA, also called "C8" which is produced when a skillet or other pan with a teflon-type anti-stick coating is over-heated, is not just in everyone's blood today, but has been found in the blood of POLAR BEARS IN THE ARCTIC!!!
     
  7. Bic_Cherry

    Bic_Cherry Active Member

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    Hi, tks for your reply.
    Firstly, are u able to reveal your % body fat or at least some OBJECTIVE fitness measure, e.g. 2.4km run timing or even insulin level, do u smoke cigarettes?

    My point per first post is that glucose tends to rise above the normal range (become diabetic) because fat cells are saturated (and therefore become relatively 'resistant ' to insulin just like a filled train cabin (there are photos on the net showing how platform guides help push people into train cabins so that more people can be transported (like sardines) vz every departing train).
    Your fat cells could be full (high % body fat) due to relatively insufficient proper exercise resulting in a raised %body fat level... which is diabetogenic.

    Not to disparage u, but just claiming to be 'very active' can be very subjective just like all armies around the world require service men to undergo proper and systermatic physical fitness tests and do not merely rely on self declared measures like 'I exercise a lot', or "my fitness is very good".

    Environmental pollutants may cause various organ compromise state but I doubt their weightage supersedes that of basic physics law (the law of conservation of energy that energy cannot be destroyed ...) thus, either ignorance or ill-discipline, (or both) are probably the principal cause of diabetes.

    BTW, muscle cells and brain cells DO NOT need any insulin for the purpose of glucose absorption.

    Liver cells filled with fat as well as swollen up fat cells of course would require more insulin to squeeze in further calories into already calorie saturated cells: thus diabetes is a self inflicted condition due to insufficiently healthy lifestyle choices.
     
    Last edited: Mar 25, 2018
  8. DoctorWho

    DoctorWho Well-Known Member

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