Vaccine questions

Discussion in 'Coronavirus (COVID-19) News' started by ronv, Dec 29, 2020.

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  1. ronv

    ronv Well-Known Member

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    My community is taking names for vaccinations.
    I was a little surprised they didn't ask if you had already had Covid.
    With the vaccine being in short supply it seems like it would be a good idea to put those people towards the end of the line.
    You're thoughts?
     
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  2. JakeJ

    JakeJ Well-Known Member Past Donor

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    If having the virus did not give you immunity, no vaccine can.
     
  3. ronv

    ronv Well-Known Member

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    Yeah. So how come?
     
  4. 557

    557 Well-Known Member

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    I would put recovered cases towards the end of the line. If I was a recovered Individual I would pass until everyone else who wanted vaccinated was covered. I think my opinion is the minority opinion. I broached the subject a while back and received quite a bit of backlash.
     
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  5. modernpaladin

    modernpaladin Well-Known Member Past Donor

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    :popcorn:
     
  6. JakeJ

    JakeJ Well-Known Member Past Donor

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    That the person didn't die means their immune system learned how to destroy the virus. Otherwise the person would have died. The claim of the vaccine is it can "mark" the virus to identify to the immune system so it will destroy it. That's the hope, anyway. But if you survived covid 19, it is a known fact your body knows how to identify and destroy the virus because it already had done it.
     
    Last edited: Dec 29, 2020
  7. fiddlerdave

    fiddlerdave Well-Known Member Past Donor

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    Last edited: Dec 29, 2020
  8. JakeJ

    JakeJ Well-Known Member Past Donor

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    Last edited: Dec 30, 2020
  9. yabberefugee

    yabberefugee Well-Known Member Past Donor

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    I may be wrong, but I heard from a friend who is in a position to know that this vaccine is not like the"flu vaccine" where virus is inject into you but rather it was designed to enhance "t" cells. Originally it was deigned in the beginning to fight cancer. I wasn't concerned at first, but when I heard this, I thought I have nothing to lose as I do have cancer. Is my friend right?
     
  10. truth and justice

    truth and justice Well-Known Member

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  11. JakeJ

    JakeJ Well-Known Member Past Donor

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    The claim covid-19 now isn't either.
     
  12. truth and justice

    truth and justice Well-Known Member

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    The Covid-19 vaccine has been shown to be effective against all the strains that were around up to November. Of course by delaying the giving of the vaccine and because of people like you, the virus is being given a longer time to mutate into a form that will have resistance to the vaccine
     
    Last edited: Dec 30, 2020
  13. ronv

    ronv Well-Known Member

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    I think it does both. Provoke an immune response which triggers T - cells.
    But lets tag @CenterField and see what he thinks.
    I think you may have some concerns if you're on chemo.
     
  14. CenterField

    CenterField Well-Known Member Past Donor

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    This vaccine is not like the flu vaccine. It doesn't contain a virus, inactivated or attenuated. It contains mRNA, that is, the instruction to make proteins. The mRNA gets into muscle cells. It instructs the cell to make the S protein, which is the virus' protein that makes its spikes (which is why this virus is called a coronavirus, corona is crown, so it has this crown of spikes - the spikes are what the virus uses to attach to and infect live cells). So, the muscle cell makes S proteins and they surface. They are seen by the immune system as "not self" and antibodies are make against the proteins. The antibodies attach to the proteins. They are then recognized by the T cells. The vaccine does cause cellular immunity too. So it is correct that it does both.

    Here, from the Pfizer phase 1/2 release:

    "All 37 participants vaccinated with BNT162b2 showed newly generated spike protein-specific CD4+ T cell responses, and almost 92% of participants demonstrated CD8+ T cell responses."

    https://www.pfizer.com/news/press-r...d-biontech-provide-data-german-phase-12-study

    Concerns about chemo: the CDC is recommending that people in this situation indeed should get vaccinated; just, they should be aware that the safety data for this situation are minimum at this point. Still, chances are that benefits outweigh risks.
     
  15. CenterField

    CenterField Well-Known Member Past Donor

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    No, the recommendation is to vaccinate everybody regardless of previous infection because the immunity caused by infection is actually erratic. People with asymptomatic illness may have little immunity. Cases of second infection are well documented at this point. It would be extremely complicated to try to verify the presence of antibodies in people. The logistics are complicated enough as they are, so the decision to just go ahead and vaccinate everybody is correct.
     
  16. CenterField

    CenterField Well-Known Member Past Donor

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    Not the only reason. It is correct that trivalent and quadrivalent flu vaccines use three or four strains, but this has nothing to do with the platform. The flu vaccine uses two platforms: inactivated virus, and live attenuated virus, the latter for the nasal spray flu vaccine.

    These mRNA Covid-19 vaccines do not contain either live attenuated, or inactivated (dead) viruses.

    The Covid-19 vaccines being developed by Sinopharm and Sinovac are with inactivated SARS-CoV-2 virus therefore are more akin to the flu shot.
     
  17. CenterField

    CenterField Well-Known Member Past Donor

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    Correct. If we were to have a rapid mass vaccination and people didn't decline the vaccine, we'd have a much bigger chance of achieving herd immunity while we can, before the virus mutates enough to evade the current vaccines.

    One good thing is that mRNA vaccines can be easily adapted to new strains, given that they are synthetic and don't need cultivation in eggs. But of course, it would mean another batch and another distribution/vaccination effort.
     
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  18. yabberefugee

    yabberefugee Well-Known Member Past Donor

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    No I'll never take chemo. Mine is a slow moving Prostate cancer, after the prostate is gone. When it matastisizes it becomes bone cancer. I don't like that idea. I'm just curious if anyone has more info, but thanks!
     
  19. ronv

    ronv Well-Known Member

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    That's what got my dad.
    Good luck.
     
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  20. truth and justice

    truth and justice Well-Known Member

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    The chemo worked for two of my uncles who had prostrate cancer, both now around 80 years old. One diagnosed about 10 years ago, the other about three years ago. Both are still alive and have no serious side effects. At least one of my uncles had part of his prostrate removed and initially had to have a catheter which caused several bouts of infection but don't think he needs a catheter now. I don't know that much about my uncle diagnosed 10 years ago but he has been cancer free for about ten years and is able to walk unaided. The other uncle also walks a lot unaided and is having regular check ups. Hope everything goes well with whichever course you decide on
     
    Last edited: Dec 30, 2020
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