COVID-19 Research, Drug trials and Pathophysiology

Yes, now that we do have efficacy data for the Oxford/AstraZeneca I guess I'd push it up to third place in my list, too.

 

I think they got the same results from bourbon.
You are still sick, you just don't care as much.

 

LOL
But no, seriously, they have hypotheses that the fluvoxamine molecule does have antiviral properties.

 

But so does the ethyl alcohol molecule.

 

And bleach! But don't drink this one, or get it by IV like a certain someone once recommended. LOL

 

n acetil cisteine could be used to combat the coronavirus.

 

This bloke was lucky.

COVID patient with sepsis makes 'remarkable' recovery following megadose of vitamin C
By national medical reporter Sophie Scott and the specialist reporting team's Lucy Kent and Loretta Florance

Updated 1hhour ago

Key points:

• Sepsis is a common cause of death for people gravely ill with COVID-19
• Researchers at the Florey Institute used megadoses of vitamin C to treat sepsis in animals
• Doctors at Austin Hospital tried the technique on a critically ill patient, who then made a "remarkable" recovery
• from the ABC (Australian Broadcasting Commission) news this morning.

 

The UK doesn't have it either. What they are using right now, was made in Belgium... while it was invented in Germany with American aid.

 

can I ask. Has any of the Pfizer vaccine been bought by the Trump administration?
And if so why is it not being distributed.

 

100 million doses have been bought and a 500 million option.
Certification will come this week

 

Cool thanks for letting me know. Good hope to all you in America then.

 

Coronavirus vaccines has been invented long time ago, it just took time to test in on humans.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284272/
The current pandemic of COVID-19 has set off an urgent search for an effective vaccine. This search may well benefit from the experiences of the animal health profession in the development and use of coronavirus vaccines in domestic animal species.


https://pubmed.ncbi.nlm.nih.gov/15742624/
Animal coronavirus vaccines: lessons for SARS

 

Thanks we will need it

 

Your first article mentions "There are two different genotypes of CCoV". So it's not just all and the same.
Some the virus name is SARS-COV-2. Seems they are just all variations of SARS.

Even Covid19 has evolved into 3 different types at the moment.
The US has mostly type A. China/South East Asia mostly type B. Europe mostly type C.
And so indeed... the US has the earliest type, that came from China.
Wuhan has mostly type B, placing doubts that it all started there.
https://www.cam.ac.uk/research/news...nalysis-provides-snapshot-of-pandemic-origins

And last time I checked,... they all started from scratch looking at the DNA of the virus and see how it ticks.

 

My point is that coronavirus is well known virus and many vaccines are used in veterinary.
There was no reason to create political hysteria, shutdown economies and borders.

 

We're not using a vaccine based on what we're giving our pets.
https://www.bbc.com/news/health-55041371

There are 230.000 dead Americans as a reason who got mislead by the US president claiming it's just a flu, it will go away like a miracle, we got this under controle. Compared to that... the not even 3000 who died during 9-11, why did we have a mass hysteria about that? People are still mourning about it...

Maybe your perception about that life aint worth it, is wrong.
How about that?

 

The vaccine existed for a long time, it was jut modified for humans.
230,000 is a lie. That number is based on statistics without adjusting it to the trends (another type of lie), real number is about 100,000

 

This little bugger contains no DNA to look at.

 

Veterinary coronavirus vaccines have little relevance to Covid. For example, bovine coronaviruses (BCoVs) are viruses that I deal with regularly. BCoV can cause respiratory and intestinal infections in cattle. We have vaccines that are pretty effective at controlling the intestinal infections, but we’ve had very limited success in controlling respiratory infection, especially in older animals as opposed to calves. Our knowledge of this virus and why vaccines have such limitations is not broad. We are still learning about the pathogen, the diseases it causes, and vaccines. I believe a better respiratory targeted BCoV vaccine is becoming available now but it’s been years in the making and I haven’t seen good data on it yet.

Since BCoV is a very different virus than SARS-CoV-2, a bovine vaccine would likely be useless for humans in any way. BCoV is not zoonotic, meaning humans can’t contract it, so a veterinary vaccine for BCoV in cattle would be very unlikely to have any cross reactivity for SARS-CoV-2 in humans.

 

Oh geez... let it be RNA. Whatever. That's just nitpicking around the fact that they made the vaccine from scratch and not by adjusting to what we've been giving our pets.

 

Of course it is useless in humans, but it does not mean it is something new.

 

You’ll notice I addressed the veterinary use of coronavirus vaccines in post #444 above. I give hundreds of coronavirus vaccines to non human species annually. and I’m well aware of the differences.

Now, these SARS-CoV-2 vaccines were not all from scratch. Much of the leg work was done in the past in the aborted effort to create vaccines for SARS and MERS. And the first mRNA vaccines were developed for use in animals.

 

Well, if we are going to go that route we’d have to say no vaccine is “new” because the first came about in the 1790’s.

 

So what that they build the easy building blocks against basically all virus pandemics in the past.
The building blocks on itself do nothing.

Really... you're just nitpicking. What's next... claiming it wasn't from scratch because there were already labs where specialized people know how to deal with viruses? Complain that the wheel was already invented when they started on the covid vaccine? Geez....

 

We agree the premise presented that claims a C19 vaccine existed or nearly existed for years is silly. But your claim the existing C19 vaccines were made from scratch is equally silly.

I’m a pragmatist on C19. I don’t like to see silly comments like both of the posters I'm responding to here have made. I’m just attempting to keep things factual.