I do fine taking 1/2 mg nightly with my other sleep stuff. and here is what Dr. Mercola has to say about Melatonin. I've been following his work and advice for many years....he is NOT MainStreamMD. https://articles.mercola.com/sites/...cid=20220814_HL2&mid=DM1237746&rid=1576061759 STORY AT-A-GLANCE Melatonin is one of the most important antioxidant molecules and certainly the most ancient, as it has been part of biological life for over 3 billion years. It's present in prokaryotes, which are bacteria, and even in plants In the human body melatonin not only has independent direct antioxidant effects on its own, but it also stimulates the synthesis of glutathione and other important antioxidants like superoxide dismutase and catalase Mitochondrial melatonin production is one of the reasons why regular sun exposure is so crucial. The near-infrared spectrum, when hitting the skin, trigger the generation of melatonin in your mitochondria Considering melatonin’s function within the mitochondria, and the fact that mitochondrial dysfunction is a hallmark of most chronic disease, it makes sense that melatonin would be helpful against a number of different diseases, including the two most common — heart disease and cancer Melatonin and methylene blue belong in every emergency medical kit. In cases of an acute heart attack or stroke, melatonin can help limit the damage, while methylene blue augments cytochromes to allow the continued production of ATP even without the use of oxygen, which also helps minimize cell death and tissue damage In this interview, Russel Reiter, Ph.D. — a world-class expert on melatonin — discusses some of the biological activities and health benefits of this important molecule. With some 1,600 papers to his credit, as well as three honorary doctor of medicine1 degrees, he’s published more studies on melatonin than anyone else alive.
