Why can't the FDA approve THIS weight loss drug?

fiddlerdave · Sep 25, 2011

[ame="http://www.youtube.com/watch?v=4RF70gWlNyw&feature=feedu"]http://www.youtube.com/watch?v=4RF70gWlNyw&feature=feedu[/ame]

Clint Torres · Sep 26, 2011

LOL good one.

waltky · Jan 10, 2012

Calories are the key to weight control...

Study Finds Calories, Not Protein, Are Key to Weight Control
January 10, 2012 - A new study may help end the perpetual debate over how best to maintain or slim down to a healthful weight. Researchers found that, while there are many elements to a good diet, carefully limiting calorie intake is the most important part of controlling one's weight.

Sixty percent of U.S. adults are overweight and more than thirty percent are obese. But Americans arent the only ones struggling with their waistlines. The World Health Organization reports that obesity has reached epidemic proportions globally, with more than one billion adults overweight. Dr. Dariush Mozaffarian studies the relationship between diet and chronic diseases at the Harvard School of Public Health. "We need a shift, a paradigm shift, in our focus on and attention to diet," Mozaffarian said. But people trying to change their eating habits and reduce their weight must sort through a bewildering variety of diets. Some recommend cutting out carbohydrates. Others say cut out the fat, eat more protein, eat less protein. The messages can be confusing.

Dr. George Bray, at the Pennington Biomedical Research Center in the southern state of Louisiana, wanted to find out if protein affects weight gain. "This study was designed to examine the effects of differing levels of protein on total calorie intake," Bray said. Twenty-five healthy adults participated in the study. Daniel Kuhn was one of them. He and the others were overfed by almost a thousand calories a day. "I was eating a lot of real butter, real whipped cream and things of that nature that I don't normally indulge in," Kuhn said.

All of the participants followed low, normal or high protein diets. The result: all of them gained weight. Fat storage was exactly the same with all three levels of protein. That is, it was the calories that they ate that affected the body fat that they stored, Bray said. But those who ate a higher percentage of protein gained more lean body mass while those on a low protein diet experienced just the opposite. If your protein intake's low, you'll actually lose body mass even though you're eating an excess amount of calories, Bray said.

Dr. Bray tells his patients to get on the scale regularly so they can catch added weight early. Dr. Mozaffarian says keeping weight in check is not just about eating less. "We don't need to go down a list of 'avoid this, avoid that,' and becoming the food police. It's mostly foods that should be increased. Its fruits, vegetables, whole grains, fish, vegetable oils and nuts," Bray said. Dr. Mozaffarian says increasing these six foods by about a serving each day would reduce obesity - and help slow the epidemic of chronic diseases associated with it. Dr. Bray's study on protein, calories and weight gain was published in the Journal of the American Medical Association.

Source
Click to expand...

V8rider · Jan 11, 2012

waltky said: ↑

Calories are the key to weight control...
Click to expand...

Which is it?

a. You did not watch the video
b. You didn't get the video
c. You forgot you were in the humor forum
d. You're a liberal

Any of the above answers would explain your post.

waltky · Oct 30, 2015

Granny says if ya want to lose weight - don't eat as much...

Low-fat diets not best for weight loss, study says
Sat, Oct 31, 2015 - Low-fat diets do not yield greater weight loss than other slimming regimes, a study said yesterday, adding to the long-running debate on how best to shed extra kilos.

A review of 53 scientific studies, covering nearly 70,000 adults in several countries, found no good evidence for recommending low-fat diets, lead author Deirdre Tobias of the Brigham and Womens Hospital in Boston, Massachusetts said. The science does not support low-fat diets as the optimal long-term weight loss strategy. In fact, low-carbohydrate diets led to greater weight loss than low-fat ones, the study published in The Lancet Diabetes & Endocrinology journal said. Weight loss on a low-fat diet was just 360g, compared with 1.15kg on a higher-fat, low-carbohydrate eating plan. As the worlds population grows ever fatter, the quest for an easy weight-loss plan has taken a high priority.

Dietary fat has long been targeted for the reason that every gram of it contains more then double the calories of a gram of carbohydrates or protein, the study said. However, research through the years has yielded contradictory results. Just last month, a small-scale study in the journal Cell Metabolism said cutting back dietary fat caused obese people to lose more body fat than restricting carbohydrates. However, the latest contribution, in the form of a meta-analysis of other studies comparing low-fat diets with other ones, found the contrary. Behind current dietary advice to cut out the fat ... the thinking is that simply reducing fat intake will naturally lead to weight loss, Tobias said in a statement. But our robust evidence clearly suggests otherwise.

Tobias said more research must be done to identify better approaches for long-term weight loss and weight maintenance. A comment on the study, published by the same journal, said it showed that weight loss overall was poor, regardless of the diet chosen. What seems to be clear is that long-term diet adherence is abysmal, irrespective of whether low-fat or other diets ... are prescribed, wrote Kevin Hall of the National Institute of Diabetes and Digestive and Kidney Diseases in Maryland. Tom Sanders of Kings College London added the best diet is to eat less and exercise more.

http://www.taipeitimes.com/News/world/archives/2015/10/31/2003631376
Click to expand...

waltky · Dec 26, 2015

Liver hormone may check sweet tooth...

Scientists find liver hormone to check sweet cravings
Friday 25th December, 2015 | WASHINGTON - Soon it may be possible to help people have better control over their 'sweet tooth' for better weight and diabetes management, as scientists have zeroed in on a hormone in the liver which suppresses the craving for candies and cakes.

While certain hormones were already known to regulate appetite, this is the first one specific to sugar consumption, according to recent studies A University of Iowa-led study in mice shows that a hormone produced by the liver, fibroblast growth factor 21 (FGF21), suppresses the consumption of simple sugars. "This is the first liver-derived hormone we know that regulates sugar intake specifically," said Dr Matthew Potthoff, the study's co-senior author and assistant professor of pharmacology in the University of Iowa in the US.

The researchers' report states that FGF21 is produced in the liver in response to high carbohydrate levels. FGF21 then enters the bloodstream, where it sends a signal to the hypothalamus region of the brain to suppress the preference for sweets. "We never imagined that a circulating, liver-derived factor would exist whose function is to control sweet appetite," states Dr Matthew Gillum, one of the scientists from the University of Copenhagen in Denmark. "We are very excited about investigating this hormonal pathway further."

The study in monkeys showed a single dose caused them to lose interest in sweetened water almost immediately. The hormone was already known to enhance insulin sensitivity, making it easier for the body to keep blood sugar at a healthy level. "Now there's this dimension where FGF21 can help people who might not be able to sense when they've had enough sugar, which may contribute to diabetes," said co-author Lucas BonDurant, a Phd student from the University of Iowa. The research showed that FGF21 did not reduce intake of all sugars - sucrose, fructose and glucose - equally, and did not affect consumption of complex carbohydrates.

One reason FGF21 existed in animals could be to improve diet quality, said the scientists. Another possibility, since sugar could ferment, was that it helped the liver protect itself from excess alcohol. The FGF21 pathway involves a molecule called carbohydrate responsive element-binding protein (ChREBP), a key regulator of glucose metabolism and fat storage. "This is the first liver-derived hormone we know that regulates sugar intake specifically," says Matthew Potthoff, assistant professor of pharmacology in the UI Carver College of Medicine. Potthoff is co-senior author on the paper, published online in the journal Cell Metabolism, with Dr Gillum.

MORE
Click to expand...

Log in or Sign up

Why can't the FDA approve THIS weight loss drug?

fiddlerdave Well-Known Member Past Donor

Clint Torres New Member

waltky Well-Known Member

V8rider New Member

waltky Well-Known Member

waltky Well-Known Member

Share This Page

Log in or Sign up

Why can't the FDA approve THIS weight loss drug?

fiddlerdave Well-Known Member Past Donor

Clint Torres New Member

waltky Well-Known Member

V8rider New Member

waltky Well-Known Member

waltky Well-Known Member

Share This Page

Useful Searches